Priere

Priere: Versatile Monophasic HA Filler with Integrated Lidocaine for Comfortable Correction

Priere, manufactured by **Hugel Inc.** (South Korea), is a **monophasic, non-animal stabilized hyaluronic acid (NASHA) dermal filler** designed for **balanced versatility** across indications from superficial radiance to moderate volumization, distinguished by its **integrated 0.3% lidocaine HCl** for enhanced patient comfort. Presented in a **1.0 ml prefilled syringe**, it contains a **high concentration (24 mg/ml) of cross-linked HA**. Priere combines predictable performance with reduced procedural discomfort.https://skin-reboot.com/

**Core Technology & Properties:**
* **Monophasic NASHA Gel:** Features a uniform, highly homogeneous, BDDE-cross-linked HA matrix (Crystal Matrix Technology™), ensuring excellent cohesion, stability, and smooth tissue integration. Minimizes clumping and promotes even distribution.
* **Medium G-Prime (Elasticity/Lift):** Provides optimal resistance to deformation for effective lifting and volumization in mid-to-deep dermal layers, while retaining sufficient malleability for natural feel and contouring.
* **High Cohesivity:** Particles bind cohesively, offering structural integrity, minimizing migration risk, and enabling smooth layering techniques.
* **Integrated Anesthetic:** **0.3% lidocaine HCl** is uniformly dispersed within the gel, significantly reducing injection pain upon delivery without altering rheological properties.
* **Optimized Viscosity & Spreadability:** Engineered for ease of injection through needles and cannulas, facilitating techniques like linear threading, fanning, and serial puncture.
* **Fine Particle Size:** Enhances suitability for superficial placement with reduced Tyndall risk when injected correctly.

**Mechanism of Action:**
1. **Volumization:** Restores lost volume in mid-to-deep dermal/subcutaneous layers (cheeks, NLFs).
2. **Fold & Line Correction:** Fills moderate nasolabial folds, marionette lines, and superficial fine lines.
3. **Contour Enhancement:** Defines and augments facial contours (cheeks, chin, jawline, lips).
4. **Hydration & Radiance:** HA binds water, improving skin hydration, elasticity, and luminosity, especially with superficial micro-droplet placement.
5. **Biostimulation:** Provides a scaffold for potential collagen and elastin production over time.

**Primary Indications:**
* **Nasolabial Folds (Mild to Moderate):** Primary indication for fold effacement.
* **Marionette Lines & Pre-jowl Sulcus:** Correcting oral commissure descent and pre-jowl hollowing.
* **Cheek Augmentation & Volumization:** Restoring midface volume and contour.
* **Lip Enhancement (Body & Border):** Adding volume and defining vermilion border.
* **Fine Lines & Skin Quality Improvement:** Superficial injection for hydration and radiance (perioral, periorbital, décolletage – micro-droplet technique).
* **Chin & Jawline Definition:** Enhancing projection and contour.
* **Dorsal Hand Rejuvenation:** Correcting volume loss.

**Key Administration Considerations:**
* **Ready-to-Use:** No reconstitution required. **Integrated 0.3% lidocaine.**
* **Anesthesia:** Integrated lidocaine provides significant pain relief. Topical or local blocks may still be used adjunctively.
* **Technique:** Highly versatile:
* **Needles:** Suitable for sharp needles (27-30G for superficial, 25-27G for deeper).
* **Cannulas:** Compatible with blunt cannulas (25-27G) for safer placement in sensitive areas (lips, NLFs).
* **Methods:** Linear threading, fanning, serial puncture, micro-droplet (superficial), bolus (deeper).
* **Depth:** **Adaptable:** Superficial dermis (micro-droplet for skin quality), mid-to-deep dermis (folds, lips), subcutaneous (volumizing cheeks/chin). *Critical to match depth to indication.*
* **Volume:** Moderate volumes. Gradual layering recommended.
* **Post-Treatment:** Swelling, redness, tenderness, bruising possible. Avoid pressure.
* **Longevity:** Typically **9-12 months**, varying with indication and depth.
* **Safety:** **Critical Risks:** **Vascular occlusion** (especially lips/NLF area – requires aspiration if needle used, cannula preferred). **Tyndall effect** if injected too superficially in certain areas. Risk of **nodules/lumps** with poor technique or overcorrection. Granuloma risk (rare). Lidocaine allergy possible (check history).
* **Regulatory Status:** **CE marked** (Europe/international). **Not FDA-approved in the USA.**
* **Prescription:** Prescription medical device.

Priere offers injectors a flexible, comfortable monophasic HA solution for diverse facial rejuvenation goals, leveraging integrated lidocaine for improved patient experience during correction from subtle radiance to structured volumization.CONTACT US